Next-generation sequencing helps you better understand
your health risks.

When it comes to your health, you don’t want to miss something important. That’s where next-generation sequencing (NGS) can play a role in giving you a more comprehensive understanding of your inherited health risks.

With NGS, AncestryHealth® is now better at identifying an increased risk for some commonly inherited conditions like breast cancer. Knowing your risk means working with your healthcare provider to get the screenings you may need for early detection.

What is NGS?

It’s a sophisticated way of analyzing your DNA. NGS is more likely to find differences in your DNA that can increase your chances of developing certain health issues. That’s because NGS looks at thousands more places in your DNA at once, compared to other genetic testing technologies that only look for a small number of them.

Designed to be offered at an affordable price, AncestryHealth® is improving access to the powerful genetic testing capability of NGS.

A simple way to
think about NGS.

DNA is like as a series of letters that creates the “book” of you.
Sometimes there are typos, or DNA differences, that are linked to certain inherited health conditions. Finding these differences requires reading your DNA.

Microarray:
Microarray technology only reads specific words.

NGS:
NGS reads whole chapters several times.

NGS reads whole chapters NGS reads whole chapters

If your book has the kind of typos that raise your risk of developing certain health conditions, NGS is a better way to find them.


Here’s how NGS stacks up.

Microarray technology
The microarray technology used by 23andMe® checks three DNA differences linked to the breast cancer genes BRCA1 and BRCA2. This results in about a 20% detection rate of those with this inherited breast cancer risk in the general U.S. population.

Microarray technology sample

NGS technology
The NGS technology used by AncestryHealth® checks thousands of places in BRCA1 and BRCA2 genes. This results in about an 80% detection rate of those with this inherited breast cancer risk in that same general U.S. population.

NGS technology sample

Because NGS looks at more places, if it does not find a DNA difference in the test, you can feel more confident that you have a lower risk for inherited breast cancer. That’s reassuring.

Keep in mind that, like all genetic testing technologies, there are limitations. NGS can rule out many of the DNA differences linked to a condition, but it can’t rule them all out.

Putting NGS to work for you and your family.

Our NGS-powered health reports are designed to help you understand the health risks for you and your family so you can take action. Each personalized report can tell you whether any DNA differences were found that put you at a higher risk for a condition you may care about, and includes a downloadable version you can take straight to a healthcare provider. Together, you can use this information to create a plan to better manage your health.


Our commitment to security and privacy.

Ancestry® does not:

  • Share genetic information with insurance companies, employers, or third-party marketers
  • Cooperate with requests by law enforcement unless legally compelled to do so. Learn more by reading our Privacy Statement.

AncestryHealth®
Learn more

1Genetic counselors are specially trained to interpret genetic test results in the context of their patients' personal and family health history. In addition to their graduate training in medical genetics and counseling, all PWNHealth genetic counselors are board certified by the American Board of Genetic Counseling (ABGC) and licensed in the states they serve.

AncestryHealth® includes laboratory tests developed and performed by an independent CLIA-certified laboratory partner, and with oversight from an independent clinician network of board-certified physicians and genetic counselors. The test results are not diagnostic and do not determine your overall chance of developing a disease or health condition. The tests are not cleared or approved by the U.S. Food and Drug Administration. You should consult a healthcare provider before taking any action based on AncestryHealth® reports, including before making any treatment, dietary, or lifestyle changes. AncestryHealth® is not currently available in New York, New Jersey and Rhode Island.