I am researching family connections to HHT. Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease and Osler–Weber–Rendu syndrome, is an autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain--and severe nosebleeds.
My husband suffers (and I do mean "suffers") from this hereditary condition. His mother, grandmother, and several cousins died from this in one form or another. Our daughter and grandson also have it.
We have traced our line back to 1870, and the marriage of William Wright (b. Mar 1837, Ohio; d. 1907, Sherman, Grayson, TX) to Mary Elizabeth Hopkins (b. 5 Feb 1837, IN; d. 29 Dec 1912, Sherman, Grayson, TX; daughter of Almon Hopkins and Margaret Young). One of these lines was the carrier, Wright or Hopkins, but we have not been able to pinpoint it further.
All three of their children, Josh, Jim, and Alice Mae Wright, were afflicted with HHT. All three died later in life from hemorrhages associated with this that they referred to as the "family bleeding disease".
If anyone can shed light on this, or wants information that we have, contact me.
Teddie Jo Linxwiler Ryanteddie.email@example.com