What Prestons are in your line? My Dad did his DNA and we believe we are Preston through his father. Long story but I am interested in comparing DNA. My Preston's are Percy Thomas Preston (1875-1941), Henry Preston (1828-1899)Colonel John Preston (1781-1864) Robert Preston (1750-1833) and John Preston (1726-1796). They were originally from Ireland and settled in the Bristol, Washington Cty Va area. Colonel John Preston also married a Preston cousin of his and they are from the Blacksburg VA area.