Thank you for your help.
Yeah, Jean seemed to have a thing for marrying women much older than him. Even his 3rd wife was a mere 42. The thing that confuses me is that even if the marriage to Joanna was annulled he was still already married to Catharina Lots when he married Joanna.
Normally when I have Flemish death records they report the spouses and previous spouses. Catharina's death record reports Jean as her spouse so I have to assume that she was his wife the entire time (1805-1827). Hopefully you are able to find poor Joanna De Schouwer's death record and we will know if he is listed as her spouse in that record as well.