Lewis Pierce was married to Harriet Thompson, but it seems as though only after he fathered children with someone else. I believe this someone else to be his first wife: Sara E Bethel.
John W Pierce, your 3rd Great-Grandfather was the 3rd oldest of Lewis' bunch. The youngest, Henry J Pierce, is my 4th great grandfather.
I would love to discuss the Pierce family with you more if you're up for it. Write me anytime: firstname.lastname@example.org