Probably a respelling of French Romain, from a personal name
(feminine Romaine) meaning ‘Roman’ (Latin Romanus),
which was borne by two martyrs and a 7th century bishop of Rouen. The
surname has been long established in French-speaking Belgium and
England (also written Romayn(e)), whence it may also have been
brought to the U.S.
Dictionary of American Family Names, Oxford University Press, ISBN 0-19-508137-4
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